This article offers a transcription and translation, as well as a commentary, on P. Mich. inv. 5594. The papyrus is believed to date from the fourth century A. D. The origin and provenance of it are unknown. The papyrus is damaged in some places, so lacunae in the text or poorly readable places are restored in accordance with the formulas and word usage on the papyri, which is always explained in the commentary. The beginning of the papyrus has been lost but the formulas at the end of it (Ἀσπάσῃ κατ̣ ’ [ὀνό]ματα… καὶ ἔ̣ρ̣ρωσό μοι) and address on the verso of the papyrus indicate that it is obviously a private letter in which a certain Lucius writes to Plution. The Nomina Sacra (θ(εο)ῦ ἐν κ(υρί)ῳ; κ(ύρι)ος) regularly repeated in this letter suggest that it was written by a Christian to a Christian. The context of the letter and the definitions pertaining to Plutio on the verso (πρεσβύτερος καὶ ὁμολογητής) suggest that the relationship between Lucius and Plutio is that of a dependent and his patron where the Lucius is being supported by a superior in age or status. As is often the case, a scrap of letter details only a moment in someone’s life, leaving us only to speculate on the context and the whole picture